Insight into the prebiotic concept – lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women
Gut. 2013 Aug;62(8):1112-21. Dewulf EM, Cani PD, Claus SP, Fuentes S, Puylaert PG, Neyrinck AM, Bindels LB, de Vos WM, Gibson GR, Thissen JP, Delzenne NM. Abstract OBJECTIVE: To highlight the contribution of the gut microbiota to the modulation of host metabolism by dietary inulin-typefructans (ITF prebiotics)
Impact of prebiotic supplementation on T-cell subsets and their related cytokines, anthropometric features and blood pressure in patients with type 2 diabetes mellitus
Complement Ther Med.2016 Feb;24:96-102. Dehghan P, Farhangi MA, Tavakoli F, Aliasgarzadeh A, Akbari AM. Abstract BACKGROUNDS AND AIMS: Type 2 diabetic mellitus (T2DM) asone of the main causes of morbidity and mortality is associated with immune system disturbances and metabolic abnormalities. In the current study
Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus a randomized controlled clinical trial
Int J Food Sci Nutr. 2014 Feb;65(1):117-23. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Abstract There is limited evidence on the effects of prebiotics on inflammation. Therefore, the aim of this study was to evaluate the effects of inulin supplementation on inflammatory
The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects
Appl Physiol Nutr Metab. 2010 Feb;35(1):9-16. Tarini J, Wolever TM. Abstract It is thought that diets high in dietary fibre are associated with reduced risk for type 2 diabetes, at least in part because the short-chainfattyacids (SCFAs) produced during the colonic fermentation of fibre beneficially influence circulating concentrations of free-fattyacids (FFAs) and
Inulin Increases Short-Term Markers for Colonic Fermentation Similarly in Healthy and Hyperinsulinemic Humans
Eur J Clin Nutr. 2011 December ; 65(12): 1279–1286. Fernandes J, Vogt J, Wolever TMS. Abstract Background/Objectives Colonic fermentation of dietary fibre produces short-chain fattyacids (SCFA) acetate, propionate and butyrate, which may protect against type 2 diabetes by reducing serum free-fatty acids (FFA). Since hyperinsulinemia is
Oligofructose-enriched inulin improves some inflammatory markers and metabolic endotoxemia in women with type 2 diabetes mellitus
Nutrition. 2014 Apr;30(4):418-23. Dehghan P, Pourghassem Gargari B, Asghari Jafar-abadi M. Abstract Objectives Anti-inflammatory therapeutic approaches are considered for the management of type2diabetes and for the prevention of its complications. There is limited evidence regarding the effects of prebiotics on inflammation, especially in patients with type2diabetes. This trial aims
The effect of enriched chicory inulin on liver enzymes, calcium homeostasis and hematological parameters in patients with type 2 diabetes mellitus
Prim Care Diabetes. 2016 Aug;10(4):265-71. Farhangi MA, Javid AZ, Dehghan P. Abstract Background and AIms Type2 diabetic mellitus (T2DM) as one of the main causes of morbidity and mortality is associated with immune system disturbances and metabolic abnormalities. In the current study we aimed to evaluate the effects of enrichedchicoryinulin supplementation
A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes
Nutr Metab (Lond). 2015 Oct 24;12:36. Guess ND, Dornhorst A, Oliver N, Bell JD, Thomas EL, Frost GS. Abstract Background Fat infiltration of the liver, muscle and pancreas is associated with insulin resistance and risk of diabetes. Weight loss reduces ectopicfat deposition and risk of diabetes, but is difficult to